DOVER — Blood Brothers, featuring Blues Music Award-winners Mike Zito and Albert Castiglia, will play The Boulevard Live Entertainment Restaurant on Saturday, courtesy of the Central Delaware Blues Society.

Both Mr. Zito and Mr. Castiglia are celebrating new albums: Mr. Zito’s double live set, “Blues for the Southside” (released Feb. 18) debuted at No. 1 on the Billboard Blues Chart, and Mr. Castiglia’s “I Got Love” was released March 25.

For the Blood Brothers tour, fans will see each band doing a set, followed by both uniting for a grand finale.

Mr. Zito is a five-time Blues Music Award winner, and Mr. Castiglia is the 2020 BMA winner for Blues Rock Album of the Year, “Masterpiece.”

With over 45 years combined in the music business, Mr. Zito and Mr. Castiglia have toured the world.

Recorded Nov. 26, 2021, at the Old Rock House in St. Louis and produced by Mr. Zito, “Blues for the Southside” showcases him on guitar and vocals, plus his band in full fury: Matthew Johnson on vocals/drums, Lewis Stephens on piano/organ and Doug Byrkit on vocals/bass. Special guests included labelmate guitarists Tony Campanella and Dave Kalz, as well as guitar wizard Eric Gales.

The song list for that night featured tunes from Mr. Zito’s earlier albums, such as “First Class Life,” “Gone to Texas,” “Make Blues Not War” and “Tribute to Chuck Berry,” plus his takes on tunes popularized by Jimi Hendrix, Stevie Ray Vaughan and Tampa Red, as well as a new song, the album’s title track.

“‘Blues for the Southside’ is a special album for me,” said Mr. Zito. “I have wanted to do a live blues album, playing songs from my catalog with my current band, for a while now. I wanted to go back to my old neighborhood in south St. Louis to make the recording. That’s where it all began for me, where I fell in love with music. I knew friends and family would fill the Old Rock House and bring the energy I was looking for in this recording.

“I wanted Tony Campanella and Dave Kalz to join me as guests. I grew up with both of these guys playing in the scene in St. Louis in the 1990s. I was surprised by my dear friend, Eric Gales, who happened to be in town for a rehearsal. He showed up, and I got him onstage to do an impromptu version of the original ‘Voodoo Chile,’ which turned out to be 12 minutes of pure guitar bliss. I am proud of this album and my band.”

Mr. Castiglia’s “I Got Love” was also produced by Mr. Zito and features a cast of musicians backing Mr. Castiglia’s guitar and vocals: Justine Tompkins (bass and vocals), Ephraim Lowell (drums and vocals) and Mr. Stephens (organ and piano).

The album showcases 11 blues-drenched tracks and is a personal statement from Mr. Castiglia.

“‘I Got Love’ is a musical essay documenting the last two years of my life: two years of many highs and lows,” he said. “It’s about falling, failing, adapting, reinventing, surviving and becoming triumphant. It contains musings of an unemployed man, a COVID-stricken idiot and getting through it like Andy Dufresne in ‘The Shawshank Redemption.’ The blues and blues-infused music is rooted in truth. This album is my truth.

“To ignore the events of the past two years and write about anything else would not be my truth. I went through it all — loss, depression, illness, fear of the unknown. I know I couldn’t have been the only one that went through it. This collection of songs is for those who felt like I did. It’s for those who went down fighting and those who keep on fighting. For many of us in my profession and in the gig economy, this was our great depression. Some of us are doing well, and some of us are still trying to find solid ground.”

The Boulevard is at 1036 Lafferty Lane, Dover.

Tickets for the 8 p.m. show are $30 and can be obtained on the Central Delaware Blues Society’s website.