BOSTON--(BUSINESS WIRE)--Jul 17, 2025--

CogniSHIELD Global, a leader in brain health and longevity, today announced Cogni SHIELD ™, a science-backed dietary supplement designed to support brain health by protecting against normal age-related cognitive decline, maximizing neural function, and promoting mental vitality, memory, and recall. Developed in collaboration with Dr. Rudolph E. Tanzi, a Harvard neuroscientist and leading expert on brain health, Cogni SHIELD ’s unique blend of ingredients were shown in laboratory studies to help the brain protect against neuroinflammation and clear away excess beta-amyloid. It’s available on Amazon and at www.CogniSHIELD.com.

Normal age-related cognitive decline can begin by age 30. Cogni SHIELD is the first commercial product conceived and tested using Alzheimer’s-in-a-Dish ™, the world’s first mini-human brain organoid model that recreates three of the main physical changes that arise in the aging brain. Dr. Tanzi tested more than 3,500 natural products at Massachusetts General Hospital using the Alzheimer’s-in-a-Dish models. The testing showed that a combination of Cogni SHIELD 's four natural ingredients—Ipriflavone, Urolithin A, Quercetin, Fisetin—demonstrated the ability to reduce neuroinflammation and clear beta-amyloid, which often accumulates in the normal aging brain. Individually, each ingredient is well-studied, found in nature and has a long history of use as a supplement. Ipriflavone and Urolithin A helped clear beta-amyloid while Quercetin and Fisetin helped reduce neuroinflammation in the Alzheimer’s-in-a-Dish laboratory models. A human study for Cogni SHIELD is expected to begin in late 2025.

“Anyone can start protecting their brain health at any age,” said George Alex, CogniSHIELD Global’s CEO. “We developed Cogni SHIELD in collaboration with one of the top neuroscientists in the world, Dr. Rudy Tanzi, to deliver a science-based supplement whose discovery and development reflects pharmaceutical rigor, which is unique for a dietary supplement. We hope it provides a valuable option for people who strive to maintain a healthy brain.”

Dr. Tanzi has written several books on brain health, including the bestsellers Super Brain, Super Genes, and The Healing Self. His research accomplishments in brain health have revolutionized understanding of age-related cognitive decline. Cogni SHIELD builds on this understanding as well as a decade-plus of testing thousands of ingredients to identify the ones with the greatest potential impact on brain health. This positions Cogni SHIELD as a potentially valuable addition to the lifestyle choices that are known to reduce the risk of dementia.

Significant published data show that lifestyle interventions can slow cognitive decline, even reducing the risk for dementia by 45 percent. Dr. Tanzi created the acronym SHIELD for the habits that can impact amyloid build up and neuroinflammation: S leep, H andling stress, I nteraction with friends, E xercise, L earning new things, and D iet. Dr. Tanzi details these lifestyle modifications on his website at www.DrRudyTanzi.com.

Cogni SHIELD is available at www.CogniSHIELD.com and at Amazon.com. A one-month supply is $89.

About Rudolph E. Tanzi, Ph.D.

Rudy Tanzi’s groundbreaking research has advanced our understanding and treatment of neurodegenerative diseases for more than four decades. He co-discovered all three genes for familial early-onset Alzheimer’s disease and co-created the novel application of human stem cells to invent the first mini-human brain, Alzheimer's-in-a-Dish, ™ which has made drug discovery significantly faster and less expensive. Dr. Tanzi is Director of the Genetics and Aging Research Unit, Director of the McCance Center for Brain Health, and Co-Director of the MassGeneral Institute for Neurodegenerative Disease at Massachusetts General Hospital. He is the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. He has received the highest awards in his field, published more than 725 research papers and co-authored several bestselling books. As a professional musician, he plays the studio keyboard for Aerosmith, Joe Perry and Johnny Depp. For additional detail, please visit his full biography. To stay abreast of his research and discoveries, visit www.DrRudyTanzi.com and follow him on LinkedIn, X and Instagram.

About Cogni SHIELD

Cogni SHIELD ™ is a science-based brain health supplement designed to support brain health by protecting against normal age-related cognitive decline, maximizing neural function, promoting brain health and mental vitality and supporting memory and recall. Cogni SHIELD ’s synergistic blend of four natural ingredients–Ipriflavone, Quercetin, Fisetin, and Urolithin A–were selected from 3500+ natural supplements and builds upon 10 years of research and testing at Massachusetts General Hospital’s Tanzi Lab. Each ingredient has been the subject of several studies supporting safety and brain health benefits. The ingredients in the vegetable-grade capsule are sourced and tested for potency, safety, and purity, and manufactured under Good Manufacturing Practices (GMP). An independent, GMP-certified laboratory conducts additional third-party testing designed to ensure quality, safety, and effectiveness. Cogni SHIELD is available at Amazon.com and www.CogniSHIELD.com.

Cogni SHIELD is a dietary supplement. Any statements about the product have not been evaluated by the U.S. Food & Drug Administration. Cogni SHIELD is not intended to diagnose, treat, cure, or prevent any disease.

About CogniSHIELD Global

CogniSHIELD Global is focused on supporting brain health as people age. Its science-based supplement, Cogni SHIELD, was developed in collaboration with Dr. Rudolph E. Tanzi, a Harvard neuroscientist and leading expert on brain health. Cogni SHIELD’s synergistic blend of four natural substances is designed to support brain health by protecting against normal age-related cognitive decline, which can begin by age 30. For more information, visit www.cognishield.com and follow the company on Instagram, Facebook and LinkedIn.

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KEYWORD: UNITED STATES NORTH AMERICA MASSACHUSETTS

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SOURCE: CogniSHIELD Global

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PUB: 07/17/2025 08:30 AM/DISC: 07/17/2025 08:31 AM

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